92511-12-1Relevant articles and documents
Synthesis of seven-membered oxacycles. Part 2: The furan approach
Fall, Yagamare,Vidal, Beatriz,Alonso, David,Gómez, Generosa
, p. 4467 - 4469 (2003)
We describe an efficient new approach for the synthesis of seven-membered oxacycles that is based on the oxidation of a furan ring with singlet oxygen followed by an intramolecular Michael addition.
NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
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, (2020/12/29)
Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a
Platinum-catalyzed α,β-unsaturated carbene formation in the formal syntheses of frondosin B and liphagal
Huynh, Khoi Q.,Seizert, Curtis A.,Ozumerzifon, Tarik J.,Allegretti, Paul A.,Ferreira, Eric M.
supporting information, p. 294 - 297 (2017/11/28)
Formal syntheses of tetracyclic terpenoids frondosin B and liphagal are described. Both synthetic routes rely on the use of platinum-catalyzed α,β-unsaturated carbene formation for the key C-C bond forming transformations. The successful route toward frondosin B utilizes a formal (4 + 3) cycloaddition, while the liphagal synthesis features the vinylogous addition of an enol nucleophile as a key step. Both synthetic routes are discussed, revealing insights into structural requirements in the catalytic a,β-unsaturated carbene reaction manifold.
