925242-27-9Relevant academic research and scientific papers
Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors
Lin, Ronghui,Johnson, Sigmond G.,Connolly, Peter J.,Wetter, Steven K.,Binnun, Eva,Hughes, Terry V.,Murray, William V.,Pandey, Niranjan B.,Moreno-Mazza, Sandra J.,Adams, Mary,Fuentes-Pesquera, Angel R.,Middleton, Steven A.
scheme or table, p. 2333 - 2337 (2009/12/07)
2,7-Diamino-thiazolo[4,5-d]pyrimidine analogues were synthesized as novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors. Representative compounds showed potent and selective EGFR inhibitory activities and inhibited in vitro cellular p
