92525-56-9Relevant academic research and scientific papers
Vinyl Isocyanate Cyclization Reactions in Synthesis. An Expedient Construction of the Octahydrophenanthridinone Ring System
Rigby, James H.,Balasubramanian, N.
, p. 4569 - 4571 (1984)
The octahydrophenanthridinone ring system is assembled in one step via a thermally induced reaction of vinyl isocyanates and enamines.
Preparation of Highly Substituted 2-Pyridones by Reaction of Vinyl Isocyanates and Enamines
Rigby, James H.,Balasubramanian, N.
, p. 224 - 228 (2007/10/02)
A method for synthesis of highly substituted 2(1H)-pyridones is reported.Vinyl isocyanates, prepared from the corresponding α,β-unsaturated carboxylic acids, undergo cyclization with various enamines to furnish six-membered heterocycles.The methodology is exemplified by numerous examples.Application of this strategy is further illustrated by the synthesis of several aza steroid analogues.
