92527-99-6

Usage

Uses

Used in Biomedical Research:
Guanosine,2'-deoxycytidylyl-(3'→5')-2'-deoxyguanylyl-(3'→5')-2'-deoxyguanylyl-(3'→5')-2'-deoxyadenylyl-(3'→5')-thymidylyl-(3'→5')-2'-deoxycytidylyl-(3'→5')-2'-deoxycytidylyl-(3'→5')-2'-deoxy(9CI) is used as a research tool for studying the structure and function of nucleic acids, as well as their role in genetic regulation and expression.
Used in Drug Development:
Guanosine,2'-deoxycytidylyl-(3'®5')-2'-deoxyguanylyl-(3'®5')-2'-deoxyguanylyl-(3'®5')-2'-deoxyadenylyl-(3'®5')-thymidylyl-(3'®5')-2'-deoxycytidylyl-(3'®5')-2'-deoxycytidylyl-(3'®5')-2'-deoxy(9CI) may be used as a potential therapeutic agent or a lead compound in the development of new drugs targeting specific genetic pathways or diseases, given its unique sequence and potential interactions with cellular machinery.
Used in Diagnostic Applications:
Guanosine,2'-deoxycytidylyl-(3'→5')-2'-deoxyguanylyl-(3'→5')-2'-deoxyguanylyl-(3'→5')-2'-deoxyadenylyl-(3'→5')-thymidylyl-(3'→5')-2'-deoxycytidylyl-(3'→5')-2'-deoxycytidylyl-(3'→5')-2'-deoxy(9CI) could be employed in the development of diagnostic tools, such as DNA or RNA probes, for detecting specific genetic sequences or mutations associated with certain diseases.
Used in Synthetic Biology:
In the field of synthetic biology, Guanosine,2'-deoxycytidylyl-(3'®5')-2'-deoxyguanylyl-(3'®5')-2'-deoxyguanylyl-(3'®5')-2'-deoxyadenylyl-(3'®5')-thymidylyl-(3'®5')-2'-deoxycytidylyl-(3'®5')-2'-deoxycytidylyl-(3'®5')-2'-deoxy- (9CI) may be utilized as a building block for designing and constructing artificial genetic systems or for engineering organisms with novel traits or functions.

Upstream product

• 78635-96-8 Phosphorochloridous acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester methyl ester 
• 78635-95-7 Phosphorochloridous acid (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester methyl ester 
• 78635-97-9 Phosphorochloridous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester methyl ester 
• 74855-51-9 Phosphorochloridous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester methyl ester 

Relevant academic research and scientific papers

SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDES USING in situ PREPARED NUCLEOSIDE METHYL PHOSPHOCHLORIDITE INTERMEDIATES

Synthesis of oligodeoxyribonucleotides on silica gel support using 5'-O-dimethoxytrityl-(N-acyl)-deoxyribonucleoside 3'-(O-methyl phosphochloridite) intermediates (I) is described.Solutions of these intermediates were prepared before use by mixing of 100 μmol-1 solution of methyl phosphodichloridite in 1,2-dichloroethane with the same volume of 120 μmol-1 solution of 5'-O-domethoxytrityl-(N-acyl)deoxyribonucleoside in 1,2-dichloroethane containing 1 mol l-1 of sym-collidine.A bench type synthesizer for this methodology is described.