925416-98-4

Upstream product

• 100-83-4 meta-hydroxybenzaldehyde 
• 110-87-2 3,4-dihydro-2H-pyran 
• 34716-73-9 3-(tetrahydro-2H-2-pyranyloxy)benzaldehyde 

Downstream Products

• 925416-99-5 C₂₀H₁₈F₃NO₃ 
• 914094-53-4 2-(3-(bromomethyl)phenoxy)tetrahydro-2H-pyran 

Relevant academic research and scientific papers

PYRAZOLO[1,5-A][1,3,5]TRIAZINE-2-AMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF

Disclosed are a pyrazolo[1,5-a][1,3,5]triazine-2-amine derivative as shown in general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative and the use of same as a therapeutic agent, in particular the use thereof as an A2a receptor antagonist and the use thereof in the preparation of drugs for treating conditions or diseases improved by the inhibition of A2a receptors.

ANDROGEN MODULATORS

The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.