92544-97-3Relevant academic research and scientific papers
C(2)-Methylation Abolishes DA1 Dopamine Agonist Activity of 2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (6,7-ADTN): Steric Intolerance by the Receptor
Nichols, David E.,Jacob, James N.,Hoffman, Andrew J.,Kohli, Jai D.,Glock, Dana
, p. 1701 - 1705 (2007/10/02)
The synthesis of 2-amino-2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene is reported.This compound did not produce vasodilation in the dog renal artery and was inactive as a DA1-type dopamine agonist.This is in contrast to the 2-nonmethyla
