925453-24-3

Upstream product

• 153800-23-8 methyl (2R,3R)-3,4-O-isopropylidene-2,3,4-trihydroxy-butyrate 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 925453-23-2 methyl (2R,3R)-3,4-(dimethylmethylenedioxy)-2-(4-methoxybenzyl)oxybutanoate 

Downstream Products

• 207124-10-5 methyl (R)-4-(tert-butyldiphenylsilyl)oxy-3-[3-(methoxymethoxy)propionyl]oxy-2-oxobutanoate 
• 925453-25-4 methyl (2R,3R)-4-(tert-butyldiphenylsilyl)oxy-2-(4-methoxybenzyl)oxy-3-[3-(methoxymethoxy)propionyl]oxybutanoate 
• 925453-26-5 methyl (2R,3R)-4-(tert-butyldiphenylsilyl)oxy-2-hydroxy-3-[3-(methoxymethoxy)propionyl]oxybutanoate 
• 440640-93-7 methyl (2R,3R)-4-(tert-butyldiphenylsilyl)oxy-3-hydroxy-2-(4-methoxybenzyl)oxybutanoate 

Relevant academic research and scientific papers

Total syntheses of zaragozic acids A and C by a carbonyl ylide cycloaddition strategy

A carbonyl ylide cycloaddition approach to the squalene synthase inhibitors zaragozic acids A and C is described. The carbonyl ylide precursor 8 was synthesized starting from di-tert-butyl D-tartrate (47) via an eleven-step sequence involving the regiosel