925692-74-6Relevant academic research and scientific papers
ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THERE OF CROSS REFERENCE TO RELATED APPLICATIONS
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Page/Page column 40; 47-48, (2011/02/24)
Compounds which exhibit antiviral activity, particularly against influenza virus,and methods of making and using there of are described herein. In one embodiment, the compounds are heterocyclic amides containing piperazine and isozazole rings and optionally substituted with one or more substituents. The compounds can be formulated with one or more pharmaceutically acceptable excipients to form compositions suitable for enteralor parenteral administration. The compounds are preferably used to treat or prevent Influenza Ainfections, such as H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, and H10N7.
ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THEREOF
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Page/Page column 13; 17, (2011/09/20)
Compounds which exhibit antiviral activity, particularly against influenza virus, and methods of making and using thereof are described herein. In one embodiment, the compounds are heterocyclic amides containing piperazine and isozazole rings and optionally substituted with one or more substituents. The compounds can be formulated with one or more pharmaceutically acceptable excipients to form compositions suitable for enteral or parenteral administration. The compounds are preferably used to treat or prevent Influenza A infections, such as H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, and H10N7.
Combinatorial synthesis of isoxazole library and their liquid crystalline properties
Tanaka, Masahiro,Haino, Takeharu,Ideta, Keiko,Kubo, Kanji,Mori, Akira,Fukazawa, Yoshimasa
, p. 652 - 665 (2007/10/03)
Six types of isoxazoles including 60 molecules were synthesized using combinatorial synthesis on solid support in a parallel fashion. Highly regioselective 1,3-dipolar cycloaddition of the nitrile oxides to the triple bond of the solid-attached ethynylben
