925921-29-5 Usage
Description
5-Tert-butoxycarbonylthiophene-2-boronic acid is an organic compound characterized by the presence of a thiophene ring with a boronic acid group at the 2-position and a tert-butoxycarbonyl group at the 5-position. This unique structure endows it with specific reactivity and properties that make it suitable for various applications in chemical synthesis and medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
5-Tert-butoxycarbonylthiophene-2-boronic acid is used as a reactant in the synthesis of oxotetrahydrofuropyrrolyl derivatives, which are known as cathepsin inhibitors. Cathepsins are a group of protease enzymes involved in various physiological processes, including immune response and tissue remodeling. Inhibition of these enzymes can be beneficial in treating diseases where cathepsin activity is implicated, such as cancer and neurodegenerative disorders.
In the synthesis of oxotetrahydrofuropyrrolyl derivatives, 5-Tert-butoxycarbonylthiophene-2-boronic acid serves as a key intermediate, providing a platform for the formation of the desired heterocyclic structure. The boronic acid group at the 2-position allows for selective functionalization and coupling reactions, while the tert-butoxycarbonyl group at the 5-position can be used for further derivatization or as a protecting group during the synthesis process.
Overall, 5-Tert-butoxycarbonylthiophene-2-boronic acid plays a crucial role in the development of novel cathepsin inhibitors, which have the potential to be used as therapeutic agents in various medical applications. Its unique structure and reactivity make it a valuable building block in the design and synthesis of bioactive compounds with potential pharmaceutical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 925921-29-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,5,9,2 and 1 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 925921-29:
(8*9)+(7*2)+(6*5)+(5*9)+(4*2)+(3*1)+(2*2)+(1*9)=185
185 % 10 = 5
So 925921-29-5 is a valid CAS Registry Number.
925921-29-5Relevant articles and documents
COMPOUNDS
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Page/Page column 116-117, (2010/11/26)
A compound of formula (I): compositions and medicaments containing the same as well as processes for the preparation and use of such compounds, compositions and medicaments, particularly in diseases associated with inappropriate Aurora activity.
