925977-75-9

Upstream product

• 925977-69-1 [1-(2,5-dimethylbenzyl)-2-[1,3]dioxolan-2-yl-ethyl]-phosphonic acid diethyl ester 
• 17053-10-0 [2-(1,3-dioxolan-2-yl)ethyl]phosphonic acid diethyl ester 

Downstream Products

• 925977-87-3 [3-(acetyl-benzyloxy-amino)-1-(2,5-dimethyl-benzyl)-propyl]-phosphonic acid diethyl ester 
• 925977-99-7 2,2-dimethyl-propionic acid [3-(acetyl-benzyloxy-amino)-1-(2,5-dimethyl-benzyl)-propyl]-(2,2-dimethyl-propionyloxymethoxy)-phosphinoyloxymethyl ester 
• 925977-93-1 2,2-dimethyl-propionic acid [3-(benzyloxy-formyl-amino)-1-(2,5-dimethyl-benzyl)-propyl]-(2,2-dimethyl-propionyloxymethoxy)-phosphinoyloxymethyl ester 

Relevant academic research and scientific papers

Arylmethyl substituted derivatives of Fosmidomycin: Synthesis and antimalarial activity

The phosphonohydroxamic acid Fosmidomycin is a drug candidate for the treatment of Malaria, currently in phase II trials in combination with Clindamycin. In order to obtain compounds of higher lipophilicity, we recently synthesized α-phenyl substituted Fo