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N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride, also known as AMTB hydrate, is a chemical compound with a complex structure that has been studied for its potential applications in various fields. It is characterized by its unique arrangement of functional groups, which contribute to its specific properties and interactions with biological systems.

926023-82-7

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926023-82-7 Usage

Uses

Used in Pharmaceutical Industry:
AMTB hydrate is used as an inhibitor of transient receptor potential cation channel, subfamily melastatin, member 8 (TRPM8) for its potential therapeutic effects in breast cancer cells and murine T cells. By targeting TRPM8, AMTB hydrate may help regulate the activity of these cells, offering a potential avenue for cancer treatment and immune modulation.

Biochem/physiol Actions

AMTB is a 2-benzyloxy-benzoic acid amide derivative, which also inhibits voltage-gated sodium channels (Nav) and their isoforms.

Check Digit Verification of cas no

The CAS Registry Mumber 926023-82-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,6,0,2 and 3 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 926023-82:
(8*9)+(7*2)+(6*6)+(5*0)+(4*2)+(3*3)+(2*8)+(1*2)=157
157 % 10 = 7
So 926023-82-7 is a valid CAS Registry Number.

926023-82-7 Well-known Company Product Price

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  • (Code)Product description
  • CAS number
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  • Sigma

  • (SML0103)  AMTB hydrate  ≥98% (HPLC)

  • 926023-82-7

  • SML0103-5MG

  • 1,130.22CNY

  • Detail
  • Sigma

  • (SML0103)  AMTB hydrate  ≥98% (HPLC)

  • 926023-82-7

  • SML0103-25MG

  • 4,559.49CNY

  • Detail

926023-82-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(3-Aminopropyl)-2-[(3-methylbenzyl)oxy]-N-(2-thienylmethyl)benz amide hydrochloride (1:1)

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:926023-82-7 SDS

926023-82-7Upstream product

926023-82-7Downstream Products

926023-82-7Relevant academic research and scientific papers

SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES TECHNICAL FIELD OF THE INVENTION

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Page/Page column 46, (2010/11/25)

The present invention relates to novel substituted 2-benzyloxy-benzoic acid amide derivatives, processes for their preparation, and their use in medicaments, especially for the prophylaxis and treatment of diseases associated with Cold Menthol Receptor 1

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