926028-84-4

Usage

Uses

Used in Pharmaceutical Industry:
5-amino-7-fluoro-1H-indole-2-carboxylic acid is used as a building block for the synthesis of biologically active molecules due to its unique chemical structure and functional groups.
Used in Drug Development:
5-amino-7-fluoro-1H-indole-2-carboxylic acid is used as a valuable intermediate in the development of new drugs, particularly for its potential to interact with biological targets such as enzymes and receptors.
Used in Biochemical and Biomedical Research:
5-amino-7-fluoro-1H-indole-2-carboxylic acid is used as a fluorescent probe in biochemical and biomedical research, taking advantage of its fluorescent properties for various analytical and diagnostic applications.

Upstream product

• 387-44-0 7-fluoro-1H-indole 
• 1167055-33-5 7-fluoro-5-nitro-1H-indole 
• 1268816-57-4 7-fluoro-5-nitroindoline 
• 926028-81-1 1-(7-fluoro-5-nitroindolin-1-yl)ethanone 
• 926028-80-0 1-(7-fluoroindolin-1-yl)ethanone 
• 769966-04-3 2,3-dihydro-7-fluoro-1H-indole 
• 926028-83-3 7-fluoro-2,3-dihydro-1H-indol-5-ylamine 

Downstream Products

• 926028-85-5 4-benzyl-1-(7-fluoro-1H-indol-5-yl)piperazine-2,6-dione 

Relevant academic research and scientific papers

5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES

The invention is directed to substituted salicylamide derivatives. Specifically, the invention is directed to compounds according to Formula (I): wherein R, R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof. The compounds of the invention are inhibitors of CD73 and can be useful in the treatment of cancer, pre-cancerous syndromes and diseases associated with CD73 inhibition, such as AIDS, the treatment of HIV, autoimmune diseases, infections, atherosclerosis, and ischemia–reperfusion injury. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting CD73 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

NOVEL 2,3-DIHYDROINDOLE COMPOUNDS

The invention relates to compounds of the formula I wherein the variables are as defined in the claims. The compounds are useful in the treatment of a disease where a D4 receptor and/or a 5-HT 2A receptor is implicated.

NOVEL 2,3-DIHYDROINDOLE COMPOUNDS

The invention relates to compounds of the formula I, wherein the variables are as defined in the claims. The compounds are useful in the treatment of a disease where a D4 receptor and/or a 5-HT2A receptor is implicated.