926028-84-4

Basic information

• Product Name: 5-amino-7-fluoro-1H-indol...
• Synonyms: 5-amino-7-fluoro-1H-indol...;5-aMino-7-fluoro-1H-indole;7-fluoro-1H-indol-5-amine
• CAS NO: 926028-84-4
• Molecular Formula: C₈H₇FN₂
• Molecular Weight: 150
• Mol File: 926028-84-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 360.6±22.0 °C(Predicted)
• Appearance: /
• Density: 1.385±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 15.94±0.30(Predicted)
• CAS DataBase Reference: 5-amino-7-fluoro-1H-indol...(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-7-fluoro-1H-indol...(926028-84-4)
• EPA Substance Registry System: 5-amino-7-fluoro-1H-indol...(926028-84-4)

Safety Data

• Hazardous Substances Data: 926028-84-4(Hazardous Substances Data)

Usage

General Description

5-amino-7-fluoro-1H-indole-2-carboxylic acid is a chemical compound with the molecular formula C9H7FN2O2. It is a derivative of indole and contains an amino group and a carboxylic acid group. 5-amino-7-fluoro-1H-indol... is of interest due to its potential pharmaceutical applications, particularly in the development of new drugs. The presence of the fluorine and amino groups makes it a useful building block for the synthesis of biologically active molecules. Furthermore, its indole moiety gives it the potential to interact with biological targets such as enzymes and receptors, making it a valuable intermediate in the pharmaceutical industry. Additionally, its fluorescent properties make it useful in biochemical and biomedical research.

Upstream product

• 926028-83-3 7-fluoro-2,3-dihydro-1H-indol-5-ylamine 
• 769966-04-3 2,3-dihydro-7-fluoro-1H-indole 
• 926028-80-0 1-(7-fluoroindolin-1-yl)ethanone 
• 926028-81-1 1-(7-fluoro-5-nitroindolin-1-yl)ethanone 
• 1268816-57-4 7-fluoro-5-nitroindoline 
• 1167055-33-5 7-fluoro-5-nitro-1H-indole 
• 387-44-0 7-fluoro-1H-indole 

Downstream Products

• 926028-85-5 4-benzyl-1-(7-fluoro-1H-indol-5-yl)piperazine-2,6-dione 

Relevant articles and documents

5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES

The invention is directed to substituted salicylamide derivatives. Specifically, the invention is directed to compounds according to Formula (I): wherein R, R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof. The compounds of the invention are inhibitors of CD73 and can be useful in the treatment of cancer, pre-cancerous syndromes and diseases associated with CD73 inhibition, such as AIDS, the treatment of HIV, autoimmune diseases, infections, atherosclerosis, and ischemia–reperfusion injury. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting CD73 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

NOVEL 2,3-DIHYDROINDOLE COMPOUNDS

The invention relates to compounds of the formula I, wherein the variables are as defined in the claims. The compounds are useful in the treatment of a disease where a D4 receptor and/or a 5-HT2A receptor is implicated.