92608-03-2Relevant academic research and scientific papers
Studies on the Synthesis of Heterocyclic Compounds. XIV. Cleavage of 1,3-Benzoxathioles by Magnesium Bromide-Acetic Anhydride
Bonsignore, Leonardo,Fadda, Anna Maria,Loy, Giuseppe,Maccioni, Anna Maria,Marongiu, Enrica,Podda, Gianni
, p. 573 - 576 (2007/10/02)
The cleavage reaction of some 1,3-benzoxathioles with magnesium bromide and acetic anhydride has been studied.In all the 1,3-benzoxathioles studied, the opening of the heterocyclic ring occurs first with cleavage of the C-O bond and formation of bromides and their corresponding products of hydrolysis.Successively also the cleavage of the C-S bond can occur.The competitive electrophilic substitution on the benzene ring becomes appreciable only in the 1,3-benzoxathioles-2,2-disubstituted with sterically demanding groups.The structure of newly prepared compounds has been determined by analytical and spectroscopic data and when possible by comparison with authentic samples.
