92615-20-8

Basic information

• Product Name: Nafenodone
• Synonyms: Nafenodone;( -)-2-(2-(Dimethylamino)ethyl)-3,4-dihydro-2-phenyl-1(2H)-naphthalenone;( -)-2-(2-(Dimethylamino)ethyl)-3,4-dihydro-2-phenyl-1(2H)-naphthalinon;Nafenodone [inn];Nafenodonum;Unii-0o501R1csq
• CAS NO: 92615-20-8
• Molecular Formula: C20H23NO
• Molecular Weight: 293.408
• Mol File: 92615-20-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 424.1°Cat760mmHg
• Flash Point: 154.2°C
• Appearance: /
• Density: 1.073g/cm³
• Vapor Pressure: 2.12E-07mmHg at 25°C
• Refractive Index: 1.571
• PKA: 9.39±0.28(Predicted)
• CAS DataBase Reference: Nafenodone(CAS DataBase Reference)
• NIST Chemistry Reference: Nafenodone(92615-20-8)
• EPA Substance Registry System: Nafenodone(92615-20-8)

Safety Data

• Hazardous Substances Data: 92615-20-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H23NO/c1-21(2)15-14-20(17-9-4-3-5-10-17)13-12-16-8-6-7-11-18(16)19(20)22/h3-11H,12-15H2,1-2H3

Upstream product

• 506-59-2 N,N-dimethylammonium chloride 

Relevant articles and documents

Efficient Synthesis of (?)-Corynoline by Enantioselective Palladium-Catalyzed α-Arylation with Sterically Hindered Substrates

Sterically hindered substrates can be employed in an enantioselective palladium-catalyzed α-arylation with the chiral monophosphorus ligand BI-DIME. This process enabled an efficient synthesis of the antidepressant (S)-nafenodone, a four-step enantioselective synthesis of the Sceletium alkaloid (+)-sceletium A-4, a concise five-step enantioselective synthesis of (?)-corynoline, as well as a three-step preparation of (?)-DeN-corynoline.