92622-05-4Relevant articles and documents
New Saponins from Phytolacca dodecandra l'Herit
Domon, Bruno,Hostettmann, Kurt
, p. 1310 - 1315 (1984)
Three bidesmosidic saponins (1-3) have been isolated from the methanolic extract of the berries of Phytolacca dodecandra l'Herit (Phytolaccaceae) by a combination of rotation locular counter-current chromatography and column chromatography on reversed phase (RP-8) with MeOH/H2O.The structures have been established by 1H-NMR, 13C-NMR, FAB-MS, and D/Cl-MS, as well as on the basis of acidic and basic hydrolyses.The monodesmosidic saponins 1a-3a obtained after partial hydrolysis with a base exhibit strong molluscicidal activity against the schistosomiasis-transmitting snail Biomphalaria glabrata.Saponins 1-3, 1a, and 3a are reported for the first time, whereas 2a has been identified previously in the aqueous extract of P. dodecandra berries.