92622-81-6 Usage
General Description
2-Bromo-benzamidine is a chemical compound with the molecular formula C7H7BrN2. It is a brominated derivative of benzamidine, which is used as a building block in organic synthesis. 2-Bromo-benzamidine is a white crystalline solid that is soluble in water and organic solvents. 2-BROMO-BENZAMIDINE is commonly used as a reagent in the synthesis of various pharmaceuticals and agrochemicals and also in the research and development of new chemical compounds. It is important to handle 2-bromo-benzamidine with care as it can be hazardous if not used properly. It is advised to use appropriate protective equipment and follow safety protocols when working with this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 92622-81-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,6,2 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 92622-81:
(7*9)+(6*2)+(5*6)+(4*2)+(3*2)+(2*8)+(1*1)=136
136 % 10 = 6
So 92622-81-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H7BrN2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,(H3,9,10)
92622-81-6Relevant articles and documents
A Highly Efficient Copper-Catalyzed Three-Component Synthesis of 4-Aminoquinazolines
Yang, Lei,Luo, Honghua,Sun, Yan,Shi, Zhenyu,Ni, Kaidong,Li, Fei,Chen, Dongyin
, p. 2535 - 2535 (2017/05/22)
A highly efficient copper-catalyzed one-pot protocol is developed for the synthesis of 4-aminoquinazolines from easily available 2-iodo- or 2-bromobenzimidamides, aldehydes, and sodium azide. This one-pot approach proceeds via consecutive copper-catalyzed SNAr substitution, reduction, cyclization, oxidation and tautomerization. The corresponding target products (26 examples) are obtained in 50-90% yield.