92644-12-7Relevant academic research and scientific papers
Conformational interactions between a phenyl ring and a side-chain halide substituent: a 1H NMR and molecular mechanics study of some 2-aryl-1-halopropanes
Cook, Michael J.,Howe, Trevor J.
, p. 957 - 965 (2007/10/02)
1H NMR data are reported for a series of 2-aryl-1-halopropanes.Vicinal coupling constants in the CH2-CH-fragment show that the rotamer populations about the C-C bond are sensitive to para substituents.The ratio of anti-gauche aryl/halide conformers is greatest when the para substituent is the electron-donating ethyl group and least when it is the strongly electron-withdrawing nitro group.This points to a non-steric conformational interaction involving the ring and the sidechain heteroatom.Comparison of the empirical results with conformational preferences predictedfrom molecular mechanics calculations using the COSMIC force field suggests that the interaction serves to enhance the population of the anti arrangement.
RELATIONSHIP GOVERNING THE ALKYLATION OF AROMATIC HYDROCARBONS WITH ALLYL CHLORIDE AND BROMIDE IN THE PRESENCE OF SULFURIC ACID
Magerramov, M. N.
, p. 1485 - 1488 (2007/10/02)
The kinetic relationships governing the alkylation of aromatic hydrocarbons by allyl chloride and allyl bromide in the presence of sulfuric acid were studied.It was established that the reactivity of the aromatic hydrocarbons varies in relation to the "activity" of the allyl halides in the order allyl chloride > allyl bromide > propylene.
