926622-03-9Relevant academic research and scientific papers
DNA interstrand crosslinking agents: Synthesis, DNA interactions, and cytotoxicity of dimeric achiral seco-amino-CBI and conjugates of achiral seco-amino-CBI with pyrrolobenzodiazepine (PBD)
Purnell, Bethany,Sato, Atsushi,O'Kelley, Amanda,Price, Carly,Summerville, Kaitlin,Hudson, Stephen,O'Hare, Caroline,Kiakos, Konstantinos,Asao, Tetsuji,Lee, Moses,Hartley, John A.
, p. 5677 - 5681 (2007/10/03)
The design and synthesis of three novel bisalkylating agents derived from the achiral seco-duocarmycin or CC-1065 analogs and pyrrolobenzodiazepines (PBDs) are described: achiral seco-CBI (cyclopropanebenz[e]indoline)-PBD 11, achiral seco-CI-PBD 12, and a
