926649-64-1

Basic information

• Product Name: Cis-5-(Tert-Butoxycarbonyl)-4,5,6,6A-Tetrahydro-3Ah-Pyrrolo[3,4-D]Isoxazole-3-Carboxylic Acid
• Synonyms: Cis-5-(Tert-Butoxycarbonyl)-4,5,6,6A-Tetrahydro-3Ah-Pyrrolo[3,4-D]Isoxazole-3-Carboxylic Acid;Cis-5-(Tert-Butoxycarbonyl)-4,5,6,6A-Tetrahydro-3Ah-Pyrrolo[3,4-D]Isoxazole-3-Carboxylic Acid(WX111690)
• CAS NO: 926649-64-1
• Molecular Formula: C11H16N2O5
• Molecular Weight: 256.25514
• Mol File: 926649-64-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cis-5-(Tert-Butoxycarbonyl)-4,5,6,6A-Tetrahydro-3Ah-Pyrrolo[3,4-D]Isoxazole-3-Carboxylic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: Cis-5-(Tert-Butoxycarbonyl)-4,5,6,6A-Tetrahydro-3Ah-Pyrrolo[3,4-D]Isoxazole-3-Carboxylic Acid(926649-64-1)
• EPA Substance Registry System: Cis-5-(Tert-Butoxycarbonyl)-4,5,6,6A-Tetrahydro-3Ah-Pyrrolo[3,4-D]Isoxazole-3-Carboxylic Acid(926649-64-1)

Safety Data

• Hazardous Substances Data: 926649-64-1(Hazardous Substances Data)

Upstream product

• 73286-70-1 N-(tert-butoxycarbonyl)-3-pyrroline 

Relevant articles and documents

Synthesis of 3-hydroxy- and 3-carboxy-Δ2-isoxazoline amino acids and evaluation of their interaction with GABA receptors and transporters

A series of 3-hydroxy- and 3-carboxy-Δ2-isoxazoline amino acids, structurally related to the GABAA agonist THIP and to the GABA uptake inhibitors THPO and exo-THPO, was prepared by means of synthetic strategies involving the 1,3-dipolar cycloaddition of nitrile oxides. All derivatives were submitted to a pharmacological investigation at both GABA receptors and transporters. Unfortunately, all amino acids were devoid of activity except for a very low affinity at GABAA receptors, displayed by compounds 8 and 17. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.