926654-16-2Relevant academic research and scientific papers
Liver-targeted prodrugs of 2′-C-methyladenosine for therapy of hepatitis C virus infection
Hecker, Scott J.,Reddy, K. Raja,Van Poelje, Paul D.,Sun, Zhili,Huang, Wenjian,Varkhedkar, Vaibhav,Reddy, M. Venkat,Fujitaki, James M.,Olsen, David B.,Koeplinger, Kenneth A.,Boyer, Serge H.,Linemeyer, David L.,MacCoss, Malcolm,Erion, Mark D.
, p. 3891 - 3896 (2008/02/13)
2′-C-Methyladenosine exhibits impressive inhibitory activity in the cell-based hepatitis C virus (HCV) subgenomic replicon assay, by virtue of intracellular conversion to the corresponding nucleoside triphosphate (NTP) and inhibition of NS5B RNA-dependent
