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Usage

Uses

Used in Pharmaceutical Industry:
L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-S-(triphenylmethyl)is used as a pharmaceutical agent for its role in enhancing protein synthesis and supporting cellular functions. The triphenylmethyl group in the compound helps protect the amino acids from degradation and allows for targeted delivery within the body, making it an important component in the development of pharmaceutical drugs.
Used in Nutritional Supplements:
L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-S-(triphenylmethyl)is used as a nutritional supplement to support various metabolic processes in the body. Its ability to enhance protein synthesis and support cellular functions makes it a valuable addition to nutritional supplements aimed at promoting overall health and well-being.
Used in Biochemical Research:
L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-S-(triphenylmethyl)is used as a research tool in biochemical studies. Its unique structure and properties make it a valuable compound for investigating various biological processes and mechanisms, contributing to the advancement of scientific knowledge in the field of biochemistry.

Upstream product

• 2799-07-7 S-trityl-L-cysteine 
• 73724-40-0 (S)-2,5-dioxopyrrolidin-1-yl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoate 

Relevant academic research and scientific papers

The use of a cysteinyl prolyl ester (CPE) autoactivating unit in peptide ligation reactions

A peptide containing a cysteinyl prolyl ester (CPE) moiety at the C-terminus (CPE peptide) is spontaneously transformed into a diketopiperazine thioester via an intramolecular N-S acyl shift reaction, followed by diketopiperazine formation. The CPE peptide can be ligated with a Cys-peptide in a one-pot procedure. The peptide diketopiperazine thioester can also be transformed into a peptide thioester by intermolecular thiol-thioester exchange with external thiol compounds such as sodium mercaptoethanesulfonate. Since CPE peptides can be prepared by standard Fmoc solid-phase synthesis, it is a versatile alternative to the peptide thioester, providing a flexible ligation strategy that promises to be useful in polypeptide synthesis.

A catalytic one-step synthesis of peptide thioacids: the synthesis of leuprorelin via iterative peptide-fragment coupling reactions

A catalytic one-step synthesis of peptide thioacids was developed. The oxygen-sulfur atom exchange reaction converted the carboxy group at the C-terminus of the peptides into a thiocarboxy group with suppressed epimerization. This method was successfully applied to the synthesis of the peptide drug leuprorelin via an iterative fragment-coupling protocol.

3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters

Peptides and proteins fragment sequence-specifically in the presence of 3-mercaptopropionic acid to afford thioesters which can be used in native chemical ligation reactions. The Royal Society of Chemistry.