926912-77-8

Basic information

• Product Name: 3-Pyrrolidinol, 4-[bis(4-methoxyphenyl)phenylmethoxy]-1-(phenylmethyl)-, (3R,4R)-
• CAS NO: 926912-77-8
• Molecular Formula: C32H33NO4
• Molecular Weight: 495.618
• Mol File: 926912-77-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyrrolidinol, 4-[bis(4-methoxyphenyl)phenylmethoxy]-1-(phenylmethyl)-, (3R,4R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyrrolidinol, 4-[bis(4-methoxyphenyl)phenylmethoxy]-1-(phenylmethyl)-, (3R,4R)-(926912-77-8)
• EPA Substance Registry System: 3-Pyrrolidinol, 4-[bis(4-methoxyphenyl)phenylmethoxy]-1-(phenylmethyl)-, (3R,4R)-(926912-77-8)

Safety Data

• Hazardous Substances Data: 926912-77-8(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 187032-53-7 (3S,4S)-1-N-benzyl-3,4-dihydroxypyrrolidine-2,6-dione 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 163439-82-5 (3R,4R)-1-benzyl-3,4-pyrrolidinediol 

Downstream Products

• 926912-80-3 (3R,4R)-1-N-benzyl-4-(4,4'-dimethoxytrityloxy)-3-mesyloxy-pyrrolidine 

Relevant articles and documents

Synthesis of diastereomeric 3-hydroxy-4-pyrrolidinyl derivatives of nucleobases

The work deals with the synthesis of hydroxypyrrolidine analogs of nucleosides. Starting from the optically pure l- or d-tartaric acid, we improved the synthesis of enantiomeric trans-3,4-dihydroxypyrrolidines and elaborated a procedure for the synthesis of all possible diastereoisomers of 3-hydroxy-4-pyrrolidinyl derivatives of both purine and pyrimidine nucleobases. The prepared compounds were tested for cytostatic and antiviral properties but no significant activity was found.