927186-01-4Relevant articles and documents
Discovery of 2-aminoimidazopyridine adenosine A2A receptor antagonists
McGuinness, Brian F.,Cole, Andrew G.,Dong, Guizhen,Brescia, Marc-Raleigh,Shao, Yuefei,Henderson, Ian,Rokosz, Laura L.,Stauffer, Tara M.,Mannava, Neelima,Kimble, Earl F.,Hicks, Catherine,White, Nicole,Wines, Pamela G.,Quadros, Elizabeth
, p. 6845 - 6849 (2010)
A novel series of adenosine A2A receptor antagonists was identified by high-throughput screening of an encoded combinatorial compound collection. The initial hits were optimized for A2A binding affinity, A1 selectivity, an
