927186-58-1

Basic information

• Product Name: 5-[2′,5′-dihydro-5′-(hydroxymethyl)-3′-[(1,1-dimethylethyl)diphenylsilyl]oxy-2′-furanyl]-3-nitro-6-[2-(4-nitrophenyl)ethoxy]-2-pyridinamine
• Synonyms: 5-[2′,5′-dihydro-5′-(hydroxymethyl)-3′-[(1,1-dimethylethyl)diphenylsilyl]oxy-2′-furanyl]-3-nitro-6-[2-(4-nitrophenyl)ethoxy]-2-pyridinamine
• CAS NO: 927186-58-1
• Molecular Weight: 656.767
• Mol File: 927186-58-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[2′,5′-dihydro-5′-(hydroxymethyl)-3′-[(1,1-dimethylethyl)diphenylsilyl]oxy-2′-furanyl]-3-nitro-6-[2-(4-nitrophenyl)ethoxy]-2-pyridinamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[2′,5′-dihydro-5′-(hydroxymethyl)-3′-[(1,1-dimethylethyl)diphenylsilyl]oxy-2′-furanyl]-3-nitro-6-[2-(4-nitrophenyl)ethoxy]-2-pyridinamine(927186-58-1)
• EPA Substance Registry System: 5-[2′,5′-dihydro-5′-(hydroxymethyl)-3′-[(1,1-dimethylethyl)diphenylsilyl]oxy-2′-furanyl]-3-nitro-6-[2-(4-nitrophenyl)ethoxy]-2-pyridinamine(927186-58-1)

Safety Data

• Hazardous Substances Data: 927186-58-1(Hazardous Substances Data)

Upstream product

• 927186-53-6 C₁₃H₁₁IN₄O₅ 

Relevant articles and documents

Ribonucleoside analogs with novel hydrogen bonding patterns

This invention relates to nucleoside, nucleotide, and oligonucleotide analogs that incorporate non-standard nucleobase analogs, defined to be those that present a pattern of hydrogen bonds to a paired nucleobase analog in a complementary strand that is different from the pattern presented by adenine, guanine, cytosine, and thymine. The invention is specifically concerned with nucleotide analogs that present the donor-donor-acceptor, hydrogen bonding patterns on pyrimidine analogs, and especially those that are analogs of ribonucleotides, including protected ribonucleotides suitable for phosphoramidite-based synthesis of RNA. The heterocycles on these nucleoside analogs are aminopyridones that have electron withdrawing groups attached to the position analogous to the 5-position of the ring in standard pyrimidines, including nitro, cyano, and carboxylic acid derivatives.