92761-46-1

Basic information

• Product Name: (7R,9R)-4-demethoxy-7-O-(2,6-dideoxy-2-iodo-α-L-mannopyranosyl)adriamycinone
• CAS NO: 92761-46-1
• Molecular Weight: 640.382
• Mol File: 92761-46-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (7R,9R)-4-demethoxy-7-O-(2,6-dideoxy-2-iodo-α-L-mannopyranosyl)adriamycinone(CAS DataBase Reference)
• NIST Chemistry Reference: (7R,9R)-4-demethoxy-7-O-(2,6-dideoxy-2-iodo-α-L-mannopyranosyl)adriamycinone(92761-46-1)
• EPA Substance Registry System: (7R,9R)-4-demethoxy-7-O-(2,6-dideoxy-2-iodo-α-L-mannopyranosyl)adriamycinone(92761-46-1)

Safety Data

• Hazardous Substances Data: 92761-46-1(Hazardous Substances Data)

Upstream product

• 73983-23-0 Acetic acid (2S,3S,4S,5R,6R)-4-acetoxy-5,6-dihydroxy-2-methyl-tetrahydro-pyran-3-yl ester 
• 65818-86-2 4-demethoxyadriamycinone 

Relevant articles and documents

Synthesis of 4-demethoxyadriamycinone utilizing ruthenium-catalyzed oxidation of allyl acetates

A new method for the construction of the side chain of anti-cancer drugs adriamycins is demonstrated by the synthesis of 4-demethoxyadriamycinone. The key step is the ruthenium-catalyzed oxidation of allyl acetates to the corresponding α-hydroxyketones.