927653-45-0 Usage
Pyrazole derivative
A derivative of pyrazole This indicates that the compound is based on the pyrazole structure, which is a five-membered heterocyclic aromatic ring containing two nitrogen atoms.
Bromine atom at the 4-position
The bromine atom is attached to the 4th carbon atom of the pyrazole ring This specifies the location of the bromine atom within the compound's structure.
Methyl group at the 1-position
A methyl group (CH3) is attached to the 1st carbon atom of the pyrazole ring This describes the presence and position of the methyl group in the compound.
4-nitrophenyl group at the 3-position
A 4-nitrophenyl group (a phenyl ring with a nitro group at the 4th position) is attached to the 3rd carbon atom of the pyrazole ring This detail outlines the presence and position of the 4-nitrophenyl group in the compound.
Used in pharmaceutical research
The compound is utilized in the study of potential drugs and medications This highlights the compound's application in the field of pharmaceuticals.
Potential biological activities
The compound is known to have possible effects on biological systems This suggests that the compound may have therapeutic or medicinal properties.
Intermediate in the synthesis of other organic compounds
The compound serves as a building block in the creation of other organic molecules This indicates its usefulness in organic synthesis and chemical reactions.
Applications in the development of new drugs
The compound may be used to create novel pharmaceuticals This points to the potential for the compound to contribute to the advancement of new medications.
Study of pyrazole derivatives for medicinal purposes
The compound is relevant in the investigation of pyrazole-based compounds for their potential therapeutic applications This emphasizes the importance of the compound in the broader context of pyrazole derivative research.
Check Digit Verification of cas no
The CAS Registry Mumber 927653-45-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,7,6,5 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 927653-45:
(8*9)+(7*2)+(6*7)+(5*6)+(4*5)+(3*3)+(2*4)+(1*5)=200
200 % 10 = 0
So 927653-45-0 is a valid CAS Registry Number.
927653-45-0Relevant academic research and scientific papers
Two convenient regioselective syntheses of 1-N-alkyl-3-aryl-4-[pyrimidin-4-yl]-pyrazoles
Ralph, Jeffrey M.,Faitg, Thomas H.,Silva, Domingos J.,Feng, Yanhong,Blackledge, Charles W.,Adams, Jerry L.
scheme or table, p. 1377 - 1380 (2009/06/08)
Two regioselective synthetic routes for 1-N-alkyl-3-aryl-4-[pyrimidin-4-yl]-pyrazoles of generic formula 1 were developed. These highly efficient and scalable routes circumvent the generally observed poor regioselectivity for the pyrazole alkylation.
AZAINDOLE INHIBITORS OF AURORA KINASES
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Page/Page column 97, (2008/06/13)
The present invention relates to a compound represented by Formula (I): and pharmaceutically acceptable salts. Compounds of the present invention inhibit Aurora kinase, making them especially suitable for the treatment of a number of diseases, including s
PYRIMIDINYL-PYRAZOLE INHIBITORS OF AURORA KINASES
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Page/Page column 59-60, (2010/11/26)
The present invention provides a compound represented by Formula (I): or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a combination thereof, wherein the substituents are as defined herein. The present invention also relates to a co
