927689-70-1

Basic information

• Product Name: (1R,2S)-2-amino-3-fluoro-1-(4-iodophenyl)propan-1-ol
• Synonyms: (1R,2S)-2-amino-3-fluoro-1-(4-iodophenyl)propan-1-ol
• CAS NO: 927689-70-1
• Molecular Formula: C₉H₁₁FINO
• Molecular Weight: 295.0926132
• Mol File: 927689-70-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1R,2S)-2-amino-3-fluoro-1-(4-iodophenyl)propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-2-amino-3-fluoro-1-(4-iodophenyl)propan-1-ol(927689-70-1)
• EPA Substance Registry System: (1R,2S)-2-amino-3-fluoro-1-(4-iodophenyl)propan-1-ol(927689-70-1)

Safety Data

• Hazardous Substances Data: 927689-70-1(Hazardous Substances Data)

Usage

Description

(1R,2S)-2-amino-3-fluoro-1-(4-iodophenyl)propan-1-ol is a chiral compound characterized by its specific stereochemistry. It is a derivative of the amino alcohol propanol, featuring a fluorine substituent at the 3 position and an iodine substituent at the 4 position of the phenyl group. This unique structure endows it with potential biological activity and makes it a promising candidate for medicinal chemistry and drug discovery.

Uses

Used in Medicinal Chemistry:
(1R,2S)-2-amino-3-fluoro-1-(4-iodophenyl)propan-1-ol is utilized as a starting material for the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Drug Discovery:
This chiral compound serves as a valuable tool in drug discovery, aiding researchers in identifying and optimizing new drug candidates with improved efficacy and selectivity.
Used in Asymmetric Synthesis:
(1R,2S)-2-amino-3-fluoro-1-(4-iodophenyl)propan-1-ol is employed in the study of asymmetric synthesis, which is crucial for the development of enantiomerically pure compounds. These compounds are essential in pharmaceuticals, as they can exhibit different biological activities and reduce potential side effects.
Used in Development of New Synthetic Methods:
(1R,2S)-2-amino-3-fluoro-1-(4-iodophenyl)propan-1-ol also plays a role in the development of new synthetic methods, which can improve the efficiency and selectivity of chemical reactions, ultimately leading to more effective and safer pharmaceutical products.

Upstream product

• 927689-69-8 4-fluoromethyl-5-(4-iodo-phenyl)-2-phenyl-4,5-dihydro-oxazole 
• 927689-68-7 [5-(4-iodo-phenyl)-2-phenyl-4,5-dihydro-oxazol-4-yl]-methanol 
• 911474-86-7 (1R,2R)-2-amino-1-(4-iodo-phenyl)-propane-1,3-diol 
• 927689-67-6 N-[2-hydroxy-1-hydroxymethyl-2-(4-iodo-phenyl)-ethyl]-acetamide 
• 39829-81-7 N-[2-(4-amino-phenyl)-2-hydroxy-1-hydroxymethyl-ethyl]-acetamide 
• 4423-58-9 N-(1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl)acetamide 
• 119-62-0 (1R,2R)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 

Downstream Products

• 1400741-13-0 2,2-dichloro-N-((1R,2S)-3-fluoro-1-hydroxy-1-(4-iodophenyl)propan-2-yl)acetamide 
• 1400740-37-5 N-{2-[4-(6-bromo-pyridin-3-yl)-phenyl]-1-fluoromethyl-2-hydroxy-ethyl}-2,2-dichloro-acetamide 
• 1400740-46-6 2,2-dichloro-N-(1-fluoromethyl-2-hydroxy-2-{4-[6-(1-methyl-1H-tetrazol-5-yl)-pyridin-3-yl]-phenyl}-ethyl)-acetamide 
• 1454906-64-9 2,2-difluoro-N-((1R,2S)-3-fluoro-1-hydroxy-1-(4-iodophenyl)propan-2-yl)acetamide 
• 1454906-65-0 2,2-difluoro-N-((1R,2S)-3-fluoro-1-hydroxy-1-(4-(trimethylstannyl)phenyl)propan-2-yl)acetamide 
• 1582261-94-6 2,2-difluoro-N-((1R,2S)-3-fluoro-1-hydroxy-1-(4-(6-(3-hydroxyoxetan-3-yl)pyridin-3-yl)phenyl)propan-2-yl)acetamide 
• 1582261-91-3 N-((1R,2S)-1-(4-(6-(2-amino-2-oxoethyl)pyridin-3-yl)phenyl)-3-fluoro-1-hydroxypropan-2-yl)-2,2-dichloroacetamide 
• 1582261-90-2 2,2-dichloro-N-((1R,2S)-1-(4-(6-(cyanomethyl)pyridin-3-yl)phenyl)-3-fluoro-1-hydroxypropan-2-yl)acetamide 
• 1582263-11-3 dibenzyl (1R,2S)-2-[(difluoroacetyl)amino]-3-fluoro-1-{4-[6-(3-hydroxyoxetan-3-yl)pyridin-3-yl]phenyl}propyl phosphate 
• 1582262-11-0 (1R,2S)-2-[(difluoroacetyl)amino]-3-fluoro-1-{4-[6-(3-hydroxyoxetan-3-yl)pyridin-3-yl]phenyl}propyl dihydrogen phosphate 
• 1582262-85-8 3-(5-{4-[(4S,5R)-3-(difluoroacetyl)-4-(fluoromethyl)-2,2-dimethyl-1,3-oxazolidin-5-yl]phenyl}pyridin-2-yl)oxetan-3-ol 
• 1582262-14-3 N-((1R,2S)-1-(4-(6-(3-aminopropanoyl)pyridin-3-yl)phenyl)-3-fluoro-1-hydroxypropan-2-yl)-2,2-difluoroacetamide 
• 1582263-15-7 tert-butyl (3-(5-(4-((4S,5R)-3-(2,2-difluoroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)phenyl)pyridin-2-yl)-3-oxopropyl)carbamate 
• 1582262-10-9 3-[5-(4-{(1R,2S)-2-[(difluoroacetyl)amino]-3-fluoro-1-hydroxypropyl}phenyl)pyridin-2-yl]oxetan-3-yl dihydrogen phosphate 

Relevant articles and documents

TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME

The present invention provides triazole macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.