92779-59-4Relevant academic research and scientific papers
Silver ion induced reactions of α-haloimines
De Kimpe, Norbert,Stevens, Christian
, p. 6753 - 6770 (2007/10/02)
The silver ion induced reactions of α-haloimines are markedly different from similar reactions with the corresponding α-haloketones. The various reactions of α-haloimines, including α-alkoxylation 1,2-dehydrohalogenation, rearrangement via α-alkoxyaziridines, Favorskii-rearrangement and Wagner Meerwein rearrangement, are compared and evaluated with silver-induced reactions of α-haloketones The silver ion assisted reactions of α-haloimines are best interpreted in terms of the intermediacy c α-imidoylcarbenium ions or pseudo-α-imidoylcarbenium ions.
Synthesis of Secondary Allylic Amines
Kimpe, Norbert de,Stanoeva, Elena,Verhe, Roland,Schamp, Niceas
, p. 587 - 592 (2007/10/02)
Secondary allylic amines were synthesized from aldehydes and primary amines via successive conversion into aldimines, α-haloaldimines and α,β-unsaturated aldimines, the latter being selectively reduced by sodium borohydride at the imino function.This method allowed the synthesis of secondary allylic amines with high preponderance of the E-stereochemistry.A comparison was made with an alternative method involving the generation of α,β-unsaturated aldimines from α,β-unsaturated aldehydes and primary amines, and subsequent borohydride reduction.
The effect of heteroatoms a the α-position of aldimines on the 1JC-H coupling constant at the sp2-carbon
Kimpe, Norbert De,Verhe, Roland,Buyck, Laurent De,Schamp, Niceas
, p. 1812 - 1816 (2007/10/02)
The effect of α-functionalization of great variety of a aldimines on the 1JC-H coupling constant at the sp2 aldimine carbon has been determined.This comparative study includes α-tert-butyl, α-alkoxy-, α-hydroxy-, α-sulfeny
