927819-53-2Relevant academic research and scientific papers
Biotransformation of sinapic acid catalyzed by Momordica charantia Peroxidase
Liu, Hai-Li,Wan, Xiang,Huang, Xue-Feng,Kong, Ling-Yi
experimental part, p. 1003 - 1008 (2009/10/01)
Biotransformation of sinapic acid (1) with H2O 2/Momordica charantia peroxidase, which exists in the widely used food M. charantia, at pH 5.0, 43 °C, in the presence of acetone resulted in six compounds, including four new compounds. Compound 2 was the first isolation of a new unique sinapic acid tetrameric derivate, which is formed by peroxidase catalysis in vitro. Besides 2, three other new sinapic acid dimers, 3-5 have also been isolated. Their structures were established on the basis of spectroscopic data. Compound 5 showed a stronger antioxidative activity than the parent sinapic acid (1). Compounds 4 and 5 significantly inhibited the growth of HL-60 cell at the concentration of 10-5 mol/L.
