927962-41-2

Basic information

• Product Name: 4-Pentynoic acid, 5-(2-aminophenyl)-, methyl ester
• CAS NO: 927962-41-2
• Molecular Formula: C12H13NO2
• Molecular Weight: 203.241
• Mol File: 927962-41-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Pentynoic acid, 5-(2-aminophenyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pentynoic acid, 5-(2-aminophenyl)-, methyl ester(927962-41-2)
• EPA Substance Registry System: 4-Pentynoic acid, 5-(2-aminophenyl)-, methyl ester(927962-41-2)

Safety Data

• Hazardous Substances Data: 927962-41-2(Hazardous Substances Data)

Upstream product

• 21565-82-2 methyl pent-4-ynoate 
• 615-43-0 2-iodophenylamine 
• 6089-09-4 4-pentynoic acid 

Relevant articles and documents

Palladium-Catalyzed Dearomatizing Difunctionalization of Indoles and Benzofurans

A palladium-catalyzed dearomatizing difunctionalization of N-Boc-indoles and benzofurans to give tricyclic indolines and 2,3-dihydrobenzofurans with a fully substituted carbon center is described. Product formation occurs under mild conditions at room temperature with commercially available aryl boronic acids and 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) as a mild oxidant in good yields. 2-Carboxyalkyl-substituted indoles and benzofurans react under Pd-catalysis with aryl boronic acids and TEMPO through dearomatizing arylation/cyclization to the corresponding indolines and dihydrobenzofurans containing a lactone moiety bearing a fully substituted carbon center.