928025-61-0 Usage
Uses
Used in Pharmaceutical Research:
(R)-1-BOC-3-ISOBUTYLPIPERAZINE is used as a key intermediate in the synthesis of various pharmaceutical compounds for the development of potential therapeutic agents. Its unique chemical structure and properties make it a valuable building block in the creation of new drugs with improved efficacy and safety profiles.
Used in Organic Synthesis:
(R)-1-BOC-3-ISOBUTYLPIPERAZINE serves as a versatile starting material in organic synthesis, allowing for the preparation of a wide range of chemical compounds. Its t-Boc protecting group can be selectively removed under mild conditions, enabling the synthesis of various piperazine-based derivatives with diverse functional groups and applications.
Used in Medicinal Chemistry:
(R)-1-BOC-3-ISOBUTYLPIPERAZINE is employed as a scaffold in medicinal chemistry for the design and optimization of novel drug candidates. Its pharmacological properties, such as anticonvulsant and psychotropic effects, make it a promising candidate for the treatment of various neurological and psychiatric disorders.
Used in Drug Development:
(R)-1-BOC-3-ISOBUTYLPIPERAZINE is utilized in drug development to explore its potential as a therapeutic agent for various diseases and conditions. Its unique chemical structure and pharmacological properties provide a foundation for the discovery of new drugs with improved therapeutic benefits and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 928025-61-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,8,0,2 and 5 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 928025-61:
(8*9)+(7*2)+(6*8)+(5*0)+(4*2)+(3*5)+(2*6)+(1*1)=170
170 % 10 = 0
So 928025-61-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H26N2O2/c1-10(2)8-11-9-15(7-6-14-11)12(16)17-13(3,4)5/h10-11,14H,6-9H2,1-5H3/t11-/m1/s1
928025-61-0Relevant academic research and scientific papers
Expedite protocol for construction of chiral regioselectively N-protected monosubstituted piperazine, 1,4-diazepane, and 1,4-diazocane building blocks
Crestey, Francois,Witt, Matthias,Jaroszewski, Jerzy W.,Franzyk, Henrik
supporting information; experimental part, p. 5652 - 5655 (2009/12/08)
(Chemical Equation Presented) This paper describes the first study of solution-phase synthesis of chiral monosubstituted piperazine building blocks from nosylamide-activated aziridines. The protocol, involving aminolysis of the starting aziridines with ω-amino alcohols and subsequent Fukuyama-Mitsunobu cyclization, offers the advantage of mild conditions as well as short reaction times, and it leads to optically pure N-Boc- or N-Ns-protected piperazines. This four-step sequence, requiring only a single final chromatographic purification, was extended to include novel diazepane and diazocane derivatives.
