928137-02-4

Basic information

• Product Name: 3-[3-(2-bromobenzyl)-3H-imidazol-4-yl]propionic acid methyl ester
• Synonyms: 3-[3-(2-bromobenzyl)-3H-imidazol-4-yl]propionic acid methyl ester
• CAS NO: 928137-02-4
• Molecular Weight: 323.189
• Mol File: 928137-02-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[3-(2-bromobenzyl)-3H-imidazol-4-yl]propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[3-(2-bromobenzyl)-3H-imidazol-4-yl]propionic acid methyl ester(928137-02-4)
• EPA Substance Registry System: 3-[3-(2-bromobenzyl)-3H-imidazol-4-yl]propionic acid methyl ester(928137-02-4)

Safety Data

• Hazardous Substances Data: 928137-02-4(Hazardous Substances Data)

Upstream product

• 102676-60-8 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanoic acid methyl ester 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 

Downstream Products

• 928137-03-5 3-[3-(2-Bromobenzyl)-3H-imidazole-4-yl]propan-1-ol 

Relevant articles and documents

Organic compounds

The present invention provides a compound of formula I: Said compound is inhibitor of aldosterone synthase and aromatase, and thus can be employed for the treatment of a disorder or disease mediated by aldosterone synthase or aromatase. Accordingly, the compound of formula I can be used in treatment of hypokalemia, hypertension, congestive heart failure, atrial fibrillation, renal failure, in particular, chronic renal failure, restenosis, atherosclerosis, syndrome X, obesity, nephropathy, post-myocardial infarction, coronary heart diseases, inflammation, increased formation of collagen, fibrosis such as cardiac or myocardiac fibrosis and remodeling following hypertension and endothelial dysfunction, gynecomastia, osteoporosis, prostate cancer, endometriosis, uterine fibroids, dysfunctional uterine bleeding, endometrial hyperplasia, polycystic ovarian disease, infertility, fibrocystic breast disease, breast cancer and fibrocystic mastopathy. Finally, the present invention also provides a pharmaceutical composition.