92844-44-5Relevant academic research and scientific papers
Synthesis of 2H-1,4-Thiazine-2,6-dicarboxylates and Their Conversion to 3,4-Pyrroledicarboxylates via Sulfur Extrusion
Lee, Len F.,Howe, Robert K.
, p. 4780 - 4783 (1984)
The reactions of 3-aminocinnamates 1c,d with S2Cl2 provided 2,5-diaryl-3,4-pyrroledicarboxylates 7c,d in 36-52percent yields whereas the reactions of 3-(perfluoroalkyl)-3-aminoacrylates 1e-h with S2Cl2 or SCl2 gave 3,5-bis(perfluoroalkyl)-2H-1,4-thiazine-
Tandem Synthesis of Tetrasubstituted NH Pyrroles from Simple Nitriles
Kim, Hyeongsu,Xuan, Zi,Hyun Kim, Ju
supporting information, p. 3336 - 3340 (2021/09/09)
An efficient tandem route to obtain tetrasubstituted NH pyrroles in a one-pot manner has been developed, staring from simple nitriles, ethyl bromoacetates, and zinc. This reaction involves oxidative dimerization of the zinc bromide complex of β-enaminoesters using cerium ammonium nitrate (CAN) as an oxidant, affording 2,3,4,5-tetrasubstituted pyrroles in yields up to 91%.
