928628-78-8Relevant articles and documents
Design-driven LO: The discovery of new ultra long acting dibasic β2-adrenoceptor agonists
Connolly, Stephen,Alcaraz, Lilian,Bailey, Andrew,Cadogan, Elaine,Christie, Jadeen,Cook, Anthony R.,Fisher, Adrian J.,Hill, Stephen,Humphries, Alexander,Ingall, Anthony H.,Kane, Zoe,Paine, Stuart,Pairaudeau, Garry,Stocks, Michael J.,Young, Alan
, p. 4612 - 4616 (2011/09/12)
Starting with the molecular scaffold of the DA2/β 2 dual agonist sibenadet (Viozan), a number of molecular changes were incorporated, which were designed to increase the potency and selectivity of the target molecule, and improve its
