928628-87-9Relevant academic research and scientific papers
Design-driven LO: The discovery of new ultra long acting dibasic β2-adrenoceptor agonists
Connolly, Stephen,Alcaraz, Lilian,Bailey, Andrew,Cadogan, Elaine,Christie, Jadeen,Cook, Anthony R.,Fisher, Adrian J.,Hill, Stephen,Humphries, Alexander,Ingall, Anthony H.,Kane, Zoe,Paine, Stuart,Pairaudeau, Garry,Stocks, Michael J.,Young, Alan
, p. 4612 - 4616 (2011/09/12)
Starting with the molecular scaffold of the DA2/β 2 dual agonist sibenadet (Viozan), a number of molecular changes were incorporated, which were designed to increase the potency and selectivity of the target molecule, and improve its
7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS β2 ADRENOCEPTOR AGONISTS
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Page/Page column 98-99, (2008/06/13)
The present invention provides compounds of formula (I) wherein the variables are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
