92864-46-5Relevant academic research and scientific papers
A Unified Approach for Divergent Synthesis of Heterocycles via TMSOTf-Catalyzed Formal [3+2] Cycloaddition of Electron-Rich Alkynes
Chen, Ping,Cao, Wei,Li, Xiangqian,Shi, Dayong
, p. 4789 - 4794 (2021)
We present a synthetic protocol for the construction of polysubstituted five-membered heterocycles via TMSOTf-catalyzed formal [3+2] cycloaddition of electron-rich alkynes, which features free from any metal, atom economy and water as the main by-product. Furthermore, alkenyl ether adduct has been verified as the key intermediate. Notably, by utilizing this approach, we can synthesize a broad range of polysubstituted furans, thiophenes and pyrroles, and extend this transformation to deliver fused-polyheterocycles. This reaction can be achieved on a gram scale and the corresponding products are intermediates for producing diverse potentially useful scaffolds. (Figure presented.).
Effect of Cationic and Nonionic Surfactants on the Reactions of Phenacyl Bromide with Some Carboxylates
Mishra, M.,Das, B. N.,Sinha, B. K.
, p. 728 - 731 (2007/10/02)
The reaction of phenacyl bromide with sodium salts of aliphatic carboxylic acids has been studied in acetone-water (72:28) mixture in the presence of varying concentrations of cationic detergent, cetyltrimethylammonium bromide (CTAB).The second-order rate
