92864-74-9Relevant academic research and scientific papers
Formation of Carbon Quaternary Stereogenic Center in Acyclic Systems via a Sequence of Carbometalation-Intramolecular Cyclization-Silicon Activation
Preshel-Zlatsin, Maya,Zhang, Fa-Guang,Eppe, Guillaume,Marek, Ilan
, p. 3279 - 3286 (2016)
The diastereoselective carbometalation reaction of cyclopropenyl esters followed by reaction with acylsilanes provides γ-silylated lactones that undergo a 'sila-Grob' fragmentation to give pyrone enolates as a new source of acyclic δ-diketones, δ-keto acid, and δ-keto ester derivatives possessing a quaternary stereocenter.
