928651-91-6Relevant articles and documents
Design and synthesis of novel bis(l-amino acid) ester prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA) with improved anti-HBV activity
Fu, Xiaozhong,Jiang, Saihong,Li, Chuan,Xin, Jian,Yang, Yushe,Ji, Ruyun
, p. 465 - 470 (2007/10/03)
A series of novel bis(l-amino acid) ester prodrugs of 9-[2-(phosphonomethoxy)ethyl] adenine (PMEA) was synthesized and their anti-HBV activity was evaluated in HepG 2 2.2.15 cells. Compounds 11, 12, 21, 22, 26, and 27 demonstrated more potent anti-HBV act