92867-95-3

Basic information

• Product Name: [1,1'-biphenyl]-4-yl(1H-imidazol-1-yl)methanone
• Synonyms: [1,1'-biphenyl]-4-yl(1H-imidazol-1-yl)methanone
• CAS NO: 92867-95-3
• Molecular Weight: 248.284
• Mol File: 92867-95-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: [1,1'-biphenyl]-4-yl(1H-imidazol-1-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-biphenyl]-4-yl(1H-imidazol-1-yl)methanone(92867-95-3)
• EPA Substance Registry System: [1,1'-biphenyl]-4-yl(1H-imidazol-1-yl)methanone(92867-95-3)

Safety Data

• Hazardous Substances Data: 92867-95-3(Hazardous Substances Data)

Upstream product

• 530-62-1 1,1'-carbonyldiimidazole 
• 92-92-2 biphenyl-4-carboxylic acid 
• 288-32-4 1H-imidazole 
• 14002-51-8 4-biphenyl-carboxylic acid chloride 

Downstream Products

• 42916-73-4 1-[1,1'-biphenyl]-4-yl-1-pentanone 
• 67035-92-1 4-biphenylcyclohexylketone 
• 92-91-1 biphenyl-4-acetaldehyde 
• 713141-13-0 3-[4'-phenylbenzoyloxy]benzoic acid 
• 933799-76-9 methyl 3-({[5-biphenyl-4-yl-3-(2,6-dichlorophenyl)isoxazol-4-ylmethoxy]benzoyl}amino)benzoate 
• 933799-62-3 methyl 3-((E)-2-{4-[5-biphenyl-4-yl-3-(2,6-dichlorophenyl)isoxazol-4-ylmethoxy]-2-chlorophenyl}vinyl)benzoate 
• 933799-70-3 4-[5-biphenyl-4-yl-3-(2,6-dichlorophenyl)isoxazol-4-ylmethoxy]-2-chlorobenzoic acid 
• 933799-48-5 4-[5-biphenyl-4-yl-3-(2,6-dichlorophenyl)isoxazol-4-ylmethoxy]-2-chlorobenzaldehyde 
• 933800-08-9 methyl 5-biphenyl-4-yl-3-(2,6-dichlorophenyl)isoxazole-4-carboxylate 
• 933799-35-0 5-biphenyl-4-yl-4-(bromomethyl)-3-(2,6-dichlorophenyl)isoxazole 
• 933800-09-0 5-biphenyl-4-yl-3-(2,6-dichlorophenyl)isoxazole-4-methanol 
• 56216-10-5 methyl 3-([1,1'-biphenyl]-4-yl)-3-oxopropanoate 
• 760175-60-8 biphenyl-4-carboxylic acid 3-benzyloxycarbonyl-phenyl ester 

Relevant articles and documents

Synthesis of 3-nitroindoles by sequential paired electrolysis

3-Nitroindoles are synthetically versatile intermediates but current methods for the preparation hinder their widespread application. Herein, we report that nitroenamines undergo electrochemical cyclisation to 3-nitroindoles in the presence of potassium iodide. Detailed control experiments and cyclic voltammogram studies infer the reaction proceedsviaa sequential paired electrolysis process, beginning with anodic oxidation of iodide (I?) to the iodine radical (I˙), which facilitates cyclisation of the nitroenamine to give a 3-nitroindolinyl radical. Cathodic reduction and protonation generates a 3-nitroindoline that upon oxidation forms the 3-nitroindole.

Organo-functionalized trimethoxysilanes featuring thioester linkage: Synthetic and UV–Vis spectral investigations

The current work reveals a series of new organo-functionalized trimethoxysilanes (OfTMS) linked via a 3C tether to the thioester group along with the inclusion of versatile aromatic and heteroaromatic sequences. The synthetic procedure implicates the one-pot thioesterification reaction of the precursor carboxylic acids (1a-r) with 3-mercaptopropyltrimethoxysilane (MPTMS), stimulated by 1,1′-carbonyldiimidazole (CDI). The OfTMS have been attentively characterized by elemental analysis, infrared and [1H, 13C] NMR spectroscopic techniques. The UV–Vis absorption behaviour demonstrates that the alkoxysilanes possess high sensitivity to the changes caused in the environment on account of different substitutions. Furthermore, the solvent effect on the absorption spectra has been scrutinized and quantified using the Kamlet-Taft approach. Importantly, the fabricated stable alkoxysilanes can be aspired for advance applications in the field of material science.

Indium-mediated one-pot synthesis of benzoxazoles or oxazoles from 2-nitrophenols or 1-aryl-2-nitroethanones

One-pot reduction-triggered heterocyclizations from 2-nitrophenols to benzoxazoles and from 1-aryl-2-nitroethanones to oxazoles were investigated. In the presence of indium/AcOH in benzene at reflux, 2-nitrophenols and R-C(OMe)3 (R=H, Me, Ph) produced excellent yields of corresponding benzoxazoles within an hour. Similarly, 1-aryl-2-nitroethanones and Ph-C(OMe)3 in the presence of indium/AcOH in acetonitrile transformed into the corresponding oxazoles with good yields.