92876-89-6Relevant academic research and scientific papers
Synthesis and biological activity of fluorinated 7-benzylamino-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amines
Dolzhenko, Anna V.,Tan, Bee Jen,Chiu, Gigi Ngar Chee,Chui, Wai Keung,Dolzhenko, Anton V.
, p. 68 - 72 (2015/04/22)
New fluorinated 7-benzylamino-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amines were designed as potential anticancer agents and a practical method for their preparation was developed. The reaction of benzhydrazide with cyanoguanidine followed by intr
A convenient method for the synthesis of 7-amino-substituted 1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amines
Dolzhenko, Anton V.,Pastorin, Giorgia,Dolzhenko, Anna V.,Chui, Wai Keung
scheme or table, p. 7180 - 7183 (2009/04/10)
A new practical synthesis of 7-amino-substituted 1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amines is developed. The triazine ring closure of 5-guanidino-3-phenyl-1,2,4-triazole with trichloroacetonitrile proceeds chemo- and regioselectively depending on the n
Practical synthesis of regioisomeric 5(7)-amino-6,7(4,5)-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazines
Dolzhenko, Anton V.,Dolzhenko, Anna V.,Chui, Wai-Keung
, p. 12888 - 12895 (2008/03/28)
A convenient and efficient synthesis of new 5-azapurine derivatives was developed. The regioisomeric 5-amino-6,7-dihydro- and 7-amino-4,5-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazines were prepared in 3-4 steps from benzhydrazide via complementary and reg
