928770-50-7Relevant articles and documents
Synthesis of 3,4-disubstituted 2H-benzopyrans through C-C bond formation via electrophilic cyclization
Worlikar, Shilpa A.,Kesharwani, Tanay,Yao, Tuanli,Larock, Richard C.
, p. 1347 - 1353 (2007)
(Chemical Equation Presented) The electrophilic cyclization of substituted propargylic aryl ethers by I2, ICl, and PhSeBr produces 3,4-disubstituted 2H-benzopyrans in excellent yields. This methodology results in vinylic halides or selenides un
Stereoselective Synthesis of Mechanically Planar Chiral Rotaxanes
Jinks, Michael A.,de Juan, Alberto,Denis, Mathieu,Fletcher, Catherine J.,Galli, Marzia,Jamieson, Ellen M. G.,Modicom, Florian,Zhang, Zhihui,Goldup, Stephen M.
supporting information, p. 14806 - 14810 (2018/10/25)
Chiral interlocked molecules in which the mechanical bond provides the sole stereogenic unit are typically produced with no control over the mechanical stereochemistry. Here we report a stereoselective approach to mechanically planar chiral rotaxanes in up to 98:2 d.r. using a readily available α-amino acid-derived azide. Symmetrization of the covalent stereocenter yields a rotaxane in which the mechanical bond provides the only stereogenic element.
