928789-34-8Relevant articles and documents
5-Oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of c-fms kinase
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Page/Page column 62-63, (2010/11/26)
The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof, wherein: W, A, Y, Z, R101 and R200 are described in the specification.