928836-81-1Relevant articles and documents
Towards Sustainable Amino Acid Derived Organocatalysts for Asymmetric syn-Aldol Reactions
Gerasimchuk, Vasiliy V.,Kucherenko, Alexandr S.,Fakhrutdinov, Artem N.,Medvedev, Michael G.,Nelyubina, Yulia V.,Zlotin, Sergei G.
, p. 2540 - 2544 (2017)
The undesirable side-processes responsible for the fast deactivation of primary amino acid derived organocatalysts in asymmetric aldol reactions are identified. A new ionic-liquid-supported (S)-valine-/(S)-α,α-diphenylserinol-derived catalyst (9) is desig
L-proline/CoCl2-catalyzed highly diastereo- and enantioselective direct aldol reactions
Karmakar, Ananta,Maji, Tapan,Wittmann, Sebastian,Reiser, Oliver
supporting information; experimental part, p. 11024 - 11029 (2011/10/31)
The CoCl2/L-proline (1:2) system was found to be an excellent catalyst for direct aldol reactions. Excellent yields (up to 93 %) and a significant improvement in diastereoselectivity (anti/syn up to 45:1) as well as enantioselectivity (up to mo
Simple and inexpensive threonine-based organocatalysts for the highly diastereo- and enantioselective direct large-scale syn-aldol and anti-Mannich reactions of α-hydroxyacetone
Wu, Chuanlong,Fu, Xiangkai,Li, Shi
experimental part, p. 1063 - 1073 (2011/10/02)
Simple and inexpensive threonine-based organocatalysts that promote syn-aldol reactions and three-component asymmetric anti-Mannich reactions of α-hydroxyacetone achieving a respectable level of enantioselectivities are reported. The syn-aldol products co
