92891-87-7Relevant academic research and scientific papers
2-SUBSTITUTED-5-HYDROXY-4H-CHROMEN-4-ONES AS NOVEL LIGANDS FOR THE SEROTONIN RECEPTOR 2B (5-HT2B)
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Page/Page column 17; 20, (2015/09/22)
A family of compounds which function as selective ligands for the serotonin receptor 2B (5-HT2B) is identified. Some of the compounds are synthetic non-natural ligands which have a relatively strong interaction with 5-HT2B compared to naturally occurring compounds (some of which are identified for the first time herein as ligands for 5-HT2B). Because the compounds, both naturally occurring and synthetically produced, function as ligands for 5-HT2B they will have application in, for example, the treatment and/or prevention of nervous system disorders such as Alzheimer's disease.
An efficient procedure for the preparation of natural products bearing the 2-(2-phenylethyl)chromone skeleton
Williams, Dwight A.,Smith, Cameron,Zhang, Yan
, p. 4292 - 4295 (2013/07/26)
Several 2-(2-phenylethyl)chromones have been shown to possess neuroprotective activity. However, limited synthetic methods have been disclosed to construct the 2-(2-phenylethyl)chromone skeleton. Herein, we report a straightforward 3-step preparation of f
A New Chromone from Agarwood and Pyrolysis Products of Chromone Derivatives
Hashimoto, Keiji,Nakahara, Sachiko,Inoue, Takehisa,Sumida, Yoshio,Takahashi, Mutsuko,Masada, Yoshiro
, p. 5088 - 5091 (2007/10/02)
A new chromone, 2-(2-4'-methoxyphenylethyl)chromone (I) was isolated together with 2-(2-phenylethyl)chromone (II: flidersiachromone) from agarwood (Japanese name; JINKOH).On pyrolysis at 150 degC, I and II were found to produce 4-methoxybenzaldehyde and b
