92893-62-4Relevant academic research and scientific papers
Angiotensin-converting enzyme inhibitors. 9. Novel [[N-(1-carboxy-3-phenylpropyl)amino]acyl]glycine derivatives with diuretic activity
Barton,Piwinski,Skiles,Regan,Menard,Desai,Golec,Reilly,Goetzen,Ueng,Warus,Schwab,Samuels,Neiss,Suh
, p. 1600 - 1606 (2007/10/02)
A series of molecules 1 having sulfonamide diuretic moieties covalently linked to non-sulfhydryl angiotensin-converting enzyme inhibitors (ACEI) were prepared and tested for both activities. IC50 values for ACEI as low as 7 nM were observed. Di
