928957-39-5

Basic information

• Product Name: N-(4-methoxyphenyl)-2-(naphthalen-2-yloxy)propionamide
• Synonyms: N-(4-methoxyphenyl)-2-(naphthalen-2-yloxy)propionamide
• CAS NO: 928957-39-5
• Molecular Weight: 321.376
• Mol File: 928957-39-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-methoxyphenyl)-2-(naphthalen-2-yloxy)propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxyphenyl)-2-(naphthalen-2-yloxy)propionamide(928957-39-5)
• EPA Substance Registry System: N-(4-methoxyphenyl)-2-(naphthalen-2-yloxy)propionamide(928957-39-5)

Safety Data

• Hazardous Substances Data: 928957-39-5(Hazardous Substances Data)

Upstream product

• 10470-82-3 2-(2-naphthalenyloxy)propanoic acid 
• 104-94-9 4-methoxy-aniline 

Relevant articles and documents

Design, synthesis and hypolipidemic activity of novel 2-(naphthalen-2-yloxy)propionic acid derivatives as desmethyl fibrate analogs

A series of 2-(naphthalen-2-yloxy)propionic acid derivatives were prepared. The hypolipidemic activity of the new compounds as well as the intermediate acid 2 was evaluated in the high cholesterol diet (HCD) fed hyperlipidemic rat model. Interestingly, the S-alkylated mercaptotriazole 8b and the 1,3,4-oxadiazole 9 produced striking reduction of serum levels of total cholesterol (TC), triglycerides (TGs) and low-density lipoproteins (LDLs) and elevation of serum high-density lipoproteins (HDLs) being more active than the reference gemfibrozil. In addition, the 1,2,4-triazole 7a, the hydroxypyrazoline 10 and the pyrazolone derivative 11 exhibited good hypolipidemic activity on different lipid parameters.