929019-95-4 Usage
Description
6-(hydroxymethyl)morpholin-3-one, also known as N-methyldiethanolamine, is a chemical compound characterized by its molecular formula C5H11NO2. It is a clear, colorless liquid with a mild amine odor, known for its versatility and valuable properties in various industrial applications.
Uses
Used in Chemical Synthesis:
6-(hydroxymethyl)morpholin-3-one is used as a solvent for the production of resins, dyes, and pharmaceuticals, facilitating the synthesis of these compounds due to its ability to dissolve a wide range of substances.
Used in Corrosion Inhibition:
In the industry, 6-(hydroxymethyl)morpholin-3-one is used as a corrosion inhibitor, protecting materials from the damaging effects of corrosive agents, thereby extending the lifespan and performance of various products and equipment.
Used in Personal Care Product Formulation:
6-(hydroxymethyl)morpholin-3-one is utilized in the formulation of personal care products, where it contributes to the product's efficacy and stability, enhancing the consumer's experience with these products.
Used as a Catalyst in Chemical Reactions:
6-(hydroxymethyl)morpholin-3-one is employed as a catalyst to accelerate chemical reactions, improving the efficiency of industrial processes and reducing the time and resources required for production.
Used in the Synthesis of Other Organic Compounds:
6-(hydroxymethyl)morpholin-3-one is also used in the synthesis of other organic compounds, highlighting its role as a versatile building block in organic chemistry and contributing to the creation of new materials and products.
Check Digit Verification of cas no
The CAS Registry Mumber 929019-95-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,9,0,1 and 9 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 929019-95:
(8*9)+(7*2)+(6*9)+(5*0)+(4*1)+(3*9)+(2*9)+(1*5)=194
194 % 10 = 4
So 929019-95-4 is a valid CAS Registry Number.
929019-95-4Relevant articles and documents
Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction
Borkin, Dmitry,Klossowski, Szymon,Pollock, Jonathan,Miao, Hongzhi,Linhares, Brian M.,Kempinska, Katarzyna,Jin, Zhuang,Purohit, Trupta,Wen, Bo,He, Miao,Sun, Duxin,Cierpicki, Tomasz,Grembecka, Jolanta
, p. 4832 - 4850 (2018/05/25)
The protein-protein interaction between menin and mixed-lineage leukemia 1 (MLL1) plays an important role in development of acute leukemia with translocations of the MLL1 gene and in solid tumors. Here, we report the development of a new generation of menin-MLL1 inhibitors identified by structure-based optimization of the thienopyrimidine class of compounds. This work resulted in compound 28 (MI-1481), which showed very potent inhibition of the menin-MLL1 interaction (IC50 = 3.6 nM), representing the most potent reversible menin-MLL1 inhibitor reported to date. The crystal structure of the menin-28 complex revealed a hydrogen bond with Glu366 and hydrophobic interactions, which contributed to strong inhibitory activity of 28. Compound 28 also demonstrates pronounced activity in MLL leukemia cells and in vivo in MLL leukemia models. Thus, 28 is a valuable menin-MLL1 inhibitor that can be used for potential therapeutic applications and in further studies regarding the role of menin in cancer.
SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR
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Page/Page column 62, (2012/09/22)
Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (Ca SR) receptors. Methods of treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (Ca SR) receptors of Formula (I).
