929047-09-6

Basic information

• Product Name: (9aS)-octahydro-1H-Pyrrolo[1,2-d][1,4]diazepine
• Synonyms: (9aS)-octahydro-1H-Pyrrolo[1,2-d][1,4]diazepine
• CAS NO: 929047-09-6
• Molecular Formula: C₈H₁₆N₂
• Molecular Weight: 140.22604
• Mol File: 929047-09-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (9aS)-octahydro-1H-Pyrrolo[1,2-d][1,4]diazepine(CAS DataBase Reference)
• NIST Chemistry Reference: (9aS)-octahydro-1H-Pyrrolo[1,2-d][1,4]diazepine(929047-09-6)
• EPA Substance Registry System: (9aS)-octahydro-1H-Pyrrolo[1,2-d][1,4]diazepine(929047-09-6)

Safety Data

• Hazardous Substances Data: 929047-09-6(Hazardous Substances Data)

Upstream product

• 929047-08-5 (9aS)-hexahydro-1H-pyrrolo[1,2-d][1,4]diazepin-2(3H)-one 

Relevant articles and documents

PYRIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS

There are provided according to the invention novel compounds of formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein: X represents a nitrogen atom; Y represents -C(H2)-, (-C(H2)-)2, -S(O2)- or -C(=O)-; Z represents -C(H2)-, -S(O2)-, -N(Rz)-, or an oxygen or sulphur atom; A represents hydrogen or -CH2OH; Rz represents hydrogen, C1-6 alkyl, C1-6 alkoxy, -COR7 or -SO2R7; R1 represents halogen, C1-6 alkyl, C1-6 alkoxy, =O, haloC1-6 alkyl, haloC1-6 alkoxy, hydroxyl or -CH2OH; m represents an integer from 0 to 3; R2 represents halogen, =O, C1-6alkyl (optionally substituted by one or more hydroxyl groups), -COOR7, -CONR7R8, C1-6 alkoxy, haloC1-6 alkyl, haloC1-6alkoxy or C1-6 alkyloC1-6 alkyl; n represents an integer from 0 to 3; p and q independently represent an integer from 0 to 2; R3 represents an -aryl, -heteroaryl, -heterocyclyl, -aryl-aryl, -aryl-heteroaryl, -aryl-heterocyclyl, -heteroaryl-aryl, -heteroaryl-heteroaryl, -heteroaryl-heterocyclyl, -heterocyclyl-aryl, -heterocyclyl-heteroaryl or -heterocyclyl-heterocyclyl group, all of which may be optionally substituted by one or more (e.g. 1, 2 or 3) halogen, C1-6 alkyl (optionally substituted by one or more hydroxyl groups), C3-8cycloalkyl, C1-6 alkoxy, hydroxyl, haloC1-6alkyl, haloC1-6 alkoxy, cyano, -S-C1-6 alkyl, -SO-C1-6 alkyl, -SO2-C1-6 alkyl, -COR7, -CONR7R8, -NR7R8, -NR7COC1-6 alkyl, -NR7SO2-C1-6alkyl, C1-6 alkyl-NR7R8, -OCONR7R8 , -NR7CO2R8 or -SO2NR7R8 groups; R4 and R5 independently represent C1-6 alkyl, or R4 and R5 together with the carbon atom to which they are attached may together form a C3-8cycloalkyl group; R6 represents halogen, C1-6 alkyl, C3-8cycloalkyl, C1-6 alkoxy, haloC1-6 alkyl or haloC1-6 alkoxy; s represents an integer from 0 to 4; R7 and R8 independently represent hydrogen, C1-6 alkyl or C3-8cycloalkyl; or solvates thereof.