929088-30-2Relevant academic research and scientific papers
Discovery of potent and selective inhibitors of 11β-HSD1 for the treatment of metabolic syndrome
Richards, Steven,Sorensen, Bryan,Jae, Hwan-soo,Winn, Marty,Chen, Yixian,Wang, Jiahong,Fung, Steven,Monzon, Katina,Frevert, Ernst U.,Jacobson, Peer,Sham, Hing,Link
, p. 6241 - 6245 (2007/10/03)
High throughput screening efforts have identified a novel class of dichloroaniline amide 11β-HSD1 inhibitors. SAR studies initiated from dichloroaniline 4 focused on retaining the potency and selectivity profile of the lead.
