929095-51-2

Usage

Uses

Used in Pharmaceutical Industry:
(R)-Methyl 5-(6-((4-Methylpiperazin-1-yl)Methyl)-1H-benzo[d]iMidazol-1-yl)-3-(1-(2-(trifluoroMethyl)phenyl)ethoxy)thiophene-2-carboxylate is used as a potential pharmaceutical candidate for the development of new drugs. Its unique structure and functional groups may contribute to its interaction with various biological targets, making it a promising compound for further research and development in the treatment of various diseases.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (R)-Methyl 5-(6-((4-Methylpiperazin-1-yl)Methyl)-1H-benzo[d]iMidazol-1-yl)-3-(1-(2-(trifluoroMethyl)phenyl)ethoxy)thiophene-2-carboxylate is used as a starting material or a structural component in the design and synthesis of novel therapeutic agents. Its diverse functional groups and structural features allow for modifications and optimizations to enhance its pharmacological properties and bioavailability.

Upstream product

• 109-01-3 1-methyl-piperazine 
• 929095-40-9 methyl 5-[6-(chloromethyl)-1H-benzimidazol-1-yl]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)thiophene-2-carboxylate 
• 929095-50-1 D-Methyl 5-(6-formyl-1H-benzimidazol-1-yl)-3-{(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxylate 
• 1094554-43-4 E-Methyl 5-({2-amino-5-[(4-methyl-1-piperazinyl)methyl]phenyl}amino)-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)-2-thiophenecarboxylate 
• 149-73-5 trimethyl orthoformate 

Relevant academic research and scientific papers

Methods For The Treatment of Central Nervous System Tumors

Methods for the treatment of primary and secondary central nervous system tumors in a mammal which comprise administration of a benzimidazole thiophene compound are provided.

Regioselective synthesis of benzimidazole thiophene inhibitors of polo-like kinase 1

A regioselective synthesis of novel 1-(2-thienyl)-benzimidazole inhibitors of polo-like kinase 1 is described. Amination of substituted 2-iodo or -bromo nitrobenzenes with a 2-aminothiophene derivative catalyzed by Pd2dba3 and XANTPH

PROCESSES FOR PREPARING BENZIMIDAZOLE THIOPHENES

A process for preparing benzimidazole thiophenes including 5-{6-[(4-methylpiperazin-1-yl)methyl]-1H-benzimidazol-1-yl}-3-{(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide.

REGIOSELECTIVE PROCESS FOR PREPARING BENZIMIDAZOLE THIOPHENES

The present invention provides a process for preparing benzimidazole thiophene compounds of formula I. Intermediates used in the process are also claimed.

BENZIMIDAZOLE THIOPHENE COMPOUNDS

The present invention provides benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.